Timelines


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(Citation 18)

GM Agriculture Timeline

By 9000-7000 BC
In Southwestern Asia,
wheat and barley were cultivated, and sheep and goats were domesticated. Dogs had been domesticated in Europe by about 10,000 BC.

 

Before 7000 BC
Grain agriculture developed in Egypt.

 

7000-3000 BC
Agriculture developed in parts of the Americas. Domesticated crops included beans,
corn (maize), cassavas, squashes, potatoes, and peppers.


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6500 BC
Cattle were domesticated in Greece.

 

6000 BC
The Huang (Yellow) River Valley was an area of early farming in northern China. Millet was a staple crops there. Rice, which may have originated in India, was cultivated throughout much of Asia by 5000 B.C.

 

About 5500 BC
In Mesopotamia, simple irrigation began and led to increased agricultural production, eventually contributing to the rise of cities.

 

By 3500 BC
Llamas were domesticated in South America. The animals were used as beasts of burden and as sources of wool and meat in some Andean areas.

 

3000 BC
The water buffalo was domesticated in India and became an important draft animal.

 

About 2500 BC
Grain agriculture formed the basis of the Harappan civilization in the Indus River Valley in present-day Pakistan and India.

 

AD 800
The open-field system of planting was common in western Europe. Village land was divided into two or three large fields, and crops were rotated in each field yearly, with one field left unplanted.

 

1400s-1500s
Explorers introduced plants and agricultural products from Asia and the Americas into Europe.
Coffee, tea, and indigo were carried back from Asia. Potatoes, tomatoes, corn (maize), and beans were among the plants brought from the Americas. Some of these plants expanded people's diets in parts of Europe.

 

Early 1700s
New crop rotation methods evolved in Europe's Low Countries and in England, improving previous systems.
Charles Townshend popularized a four-field system in Norfolk County, England. He found that turnips could be rotated with wheat, barley, clover, and ryegrass to make soil more fertile and increase yields.

 

1701
Jethro Tull introduced the seed drill to English farmers. The device, which cut furrows and dropped in seeds, ended the slow, laborious task of sowing seeds by hand for many people.

 

Late 1700s
In England, Robert Bakewell pioneered the selective breeding of cattle and sheep to produce meatier animals.

 

1793
In the United States, Eli Whitney invented the cotton gin, a machine that separated fiber from seed much more quickly than people could do it by hand.

 

1834
In the United States, the first practical reaper, or grain harvesting machine, was patented by Cyrus McCormick.

 

1837
In the United States,
John Deere patented the steel plow. It was stronger, sharper, and more efficient than wooden or iron plows. Heavy damp soil did not stick to it as readily.

 

1842
In England, Sir John Bennet Lawes founded the first factory to manufacture superphosphate. This marked the beginning of the chemical fertilizer industry.

 

1850s-Early 1900s
Railroad and steamship lines were expanded, opening up new markets. Improved methods of refrigeration and canning made possible the long-distance shipping of perishable agricultur

al products.

1866
The results of
Gregor Mendel's studies in heredity were published in Austria. In experiments with pea plants, Mendel learned how traits were passed from one generation to the next. His work paved the way for improving crops through genetics.

 

Early 1890s
The first gasoline-powered tractors were built. They gradually replaced steam-powered tractors and draft animals in many parts of the world.

 

1890s
The combine harvester, which combined the cutting and threshing of grain crops, came into widespread use in California. It gradually spread to other western states. The combine reduced the amount of labor needed to harvest one hectare of wheat from 37 to 6.25 man-hours.

 

1920s
Better nutrition, disease control measures, and breeding practices greatly improved livestock production in many countries.

 

Late 1920s
Scientists improved the seeds from which farmers grew corn. The best qualities of several kinds of seeds were combined. Fertilizers helpted farmers produce more from each plant.

 

1935
The U.S. Rural Electrification Administration was established. Electricity became more readily available in rural areas.

 

1939
DDT was introduced, marking the beginning of agriculture's heavy use of chemical pesticides in developing countries. The U.S. banned DDT in 1972 because it was harming the environment.

 

1945-About 1970
Machines and increased productivity in industrialized countries sharply reduced the number of people working in agriculture. Through scientific advances and improved management techniques, farmers produced more food than ever before.


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1950s-1960s
Several developing countries, such as India and the Philippines, experienced the green revolution. High-yield grains were introduced, greatly increasing production and local supplies.

 

1970s-Present
Researchers in California first spliced a gene from one organism into another, and the age of genetic engineering began. Genetic engineering offers the possibility of making plants and animals hardier, more resistant to disease, and more productive.

 

Early 1980s
In developed countries, farmers began using computers to keep farm accounts; to monitor crop prices and weather conditions; to help decide when to irrigate and plant; and to automate the application of fertilizers and pesticides.

 

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(Citation 20)

1953 - Structure of DNA deduced (Watson, Crick, Wilkins, Franklin)

1968 - DNA code deciphered

1973 - First recombinant DNA experiments (in bacteria)

1978 - First in vitro fertilization birth

1978 - First germline-engineered mammals (mice)

1980 - US Supreme Court rules in favor of patents on genetically engineered organisms (Chakrabarty decision)

1982 - First proposals for human gene transfer experiments

1988 - Launch of Human Genome Project

1991 - First somatic gene transfer experiments begun

1992 - Development of intra-cytoplasmic sperm injection (ICSI) in Belgium

1995 - W. French Anderson and colleagues awarded a US patent on all ex vivo gene manipulations in humans

1996 - First mammal cloned (sheep)


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1997 - An anonymous private donor (later revealed to be John Sperling) commissions Texas A&M University to clone a pet dog

1998 - W. French Anderson submits first proposal involving human germline modification to the Recombinant DNA Advisory Committee of the National Institutes of Health

1999 - Human artificial chromosomes under development

1999 - Texas A&M University clones the first bull

February 2000 - Genetic Savings and Clone is founded, initially to store samples for later cloning of pets

March 2000 - A pig is cloned

June 2000 - "Working draft" of the human genome sequence announced

October 2000 - A child conceived in part to provide therapeutic tissues for an earlier-born sibling is born; techniques of preimplantation genetic diagnosis are used to ensure that the child does not itself carry the disease

December 2000 - UK newspapers report that a patent for genetically modified sperm has been issued to fertility researchers

December 2000 - Members of the Raelian sect announce their intention to clone a human being within the coming year

January 2001 - Scientists in Oregon announce the first transgenic primate, a rhesus monkey engineered with jellyfish genes; Eduardo Kac publicizes the creation of a rabbit genetically modified to glow green under florescent light as a work of art

February 2001 - Wired magazine reports that several covert efforts to clone human beings are underway

February 2001 - Fertility researchers Severino Antinori and Panos Zavos announce their intention to clone a human being within a year

March 2001 - Researchers at the St. Barnabas Medical Center in New Jersey announce their use of ooplasmic transfer techniques, arguably a form of germline genetic engineering, as an infertility treatment

July 2001 - The Jones Institute for Fertility in Virginia announces the creation of human embryos for experimental uses. Advanced Cell Technologies (ACT) in Massachusetts acknowledges attempts to create clonal human embryos

October 2001 - Fertility experts announce they will begin to offer PGD for use in sex selection to clients

November 2001 - Advanced Cell Technology (ACT) announces that its researchers have produced cloned human embryos; most scientists consider the experiment a failure and the announcement premature at best


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February 2002 - Scientists at Texas A&M University announce that they cloned a cat in December, the first cloning of a house pet

March 2002 - China reported to be creating human clonal embryos for research

November 2002 - Gene scientist J. Craig Venter and Hamilton Smith, a Nobel laureate, announce they intend to create a single-celled organism with the minimum number of genes necessary to sustain life

December 2002 - Clonaid and Raelians claim to have created human clones, but later this is shown to be a hoax

February 2003 - Scientists genetically modify human stem cells

April 2003 - Research on primates suggests that successful human cloning may be impossible

April 2003 - The first complete sequence of the genetic code of a single human, claimed to be accurate to 99.999%, is announced

May 2003 - A mule is cloned

July 2003 - A controversial fertility specialist announces that he has created mixed-sex chimeras by transplanting male cells into one-day-old female embryos

August 2003 - A horse is cloned

August 2003 - Chimeric stem cells are reported to have been derived from hybrid rabbit-human cloned embryos

August 2003 - A rat is cloned

December 2003 - Researchers grow mouse sperm cells from stem cells and fertilize an egg

January 2004 - A team of Japanese and US researchers create zebrafish from sperm that had been genetically modified and grown in culture

February 2004 - Korean researchers led by Hwang Woo Suk announce that they have succeeded in cloning human embryos and extracting stem cells from them

April 2004 - Genetics Savings and Clone offers cat cloning commercially

April 2004 - A mouse is born with two female parents and no male parent.

May 2004 - Announcement or the birth of siblings selected with the use of preimplantation genetic diagnosis (PGD) to provide stem cells for children suffering from non-genetic diseases

August 2004 - A team of scientists at the University of Newcastle in the United Kingdom begins work on research cloning

May 2005 - Korean researchers led by Hwang Woo Suk announce the successful derivation of eleven patient-specific stem cell lines using cloning techniques; this is said to be accompanied by a great improvement in the efficiency in the cloning process

May 2005 - Newcastle researchers announced they have cloned human embryos, though none lasted longer than five days and no embryonic stem cells were derived from them

January 2006 - The journal Science retracts the claims of scientists led by Hwang Woo Suk about research cloning; Hwang is also accused of coercing subordinate women to provide their eggs for his work, of fabricating data, and of embezzling research funds provided by the South Korean government

June 2006 - A team of scientists at Harvard University begins research cloning

July 2006 - Scientists in Newcastle announce they have produced mice with artificial sperm derived from embryonic stem cells; all the mice are defective, infertile and short-lived but this is said to point the way to treatment of male infertility.

August 2006 - Scientists at Advanced Cell Technology claim to have isolated embryonic stem cells without destroying the embryo; their claims are soon largely refuted

October 2006 - Genetic Savings and Clone closes, due to lack of demand for cloned pets